Ng, Daniel Zhi Wei
Yap, Gaik Chin
Tay, Carina Jing Xuan
Huang, Chiung-Hui
Zhao, Siyan
Low, Adrian
Tham, Elizabeth Huiwen
Loo, Evelyn Xiu Ling
Shek, Lynette P.
Goh, Anne
Chong, Kok Wee
Goh, Si Hui
Cheng, Zai Ru
Van Bever, Hugo P. S.
Teoh, Oon Hoe
Lee, Yung Seng
Yap, Fabian
Tan, Kok Hian
Chong, Yap-Seng
Chan, Shiao-Yng
Eriksson, Johan Gunnar
Godfrey, Keith M.
Lay, Christophe
Knol, Jan
Schuster, Stephan C.
Lai, Jun Shi
Chong, Mary Foong-Fong
Lee, Jonathan Wei Jie
Lee, Bee Wah
Chan, Eric Chun Yong https://orcid.org/0000-0001-6107-9072
Ta, Le Duc Huy https://orcid.org/0000-0001-8579-0125
Funding for this research was provided by:
Medical Research Council (MC_UU_12011/4)
National Institute for Health and Care Research (NIHR Senior Investigator (NF-SI-0515-10042) and NIHR Southampton Biomedical Research Centre (NIHR203319))
Rosetrees Foundation
Singapore Ministry of Health’s National Medical Research Council Clinician Scientist – Individual Research Grant (MOH-000532)
Article History
Received: 12 July 2025
Accepted: 7 April 2026
First Online: 17 April 2026
Declarations
:
: The study was performed in accordance with the Declaration of Helsinki and ethics approval was obtained from the SingHealth Centralized Institutional Review Board (reference 2014/692/D). All study participants provided written consent. The study has been registered at ClinicalTrials.gov (NCT 03531658).
: Not applicable.
: Authors CL and JK are employees of Danone Research and Innovation. The remaining authors declare that they have no competing interests.