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Authors
Wang, Yi https://orcid.org/0000-0001-6965-9696
Xue, Xiaonan
Usyk, Mykhaylo
Sharma, Anjali
Anastos, Kathryn
Post, Wendy S.
Hodis, Howard N.
Wang, Zheng
Witt, Mallory D.
Rinaldo, Charles R.
Brown, Todd T.
Palella, Frank J.
Gange, Stephen
Kuniholm, Mark H.
Sha, Beverly E.
Caron, Patrick
Gerszten, Robert E.
Clish, Clary B.
Guillemette, Chantal
Burk, Robert D.
Kaplan, Robert C.
Qi, Qibin
Hanna, David B.
Peters, Brandilyn A.
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Funding
Funding for this research was provided by:
National Heart, Lung, and Blood Institute (R01HL095129)
National Heart, Lung, and Blood Institute (K01HL169019)
National Heart, Lung, and Blood Institute (R01HL148094)
National Heart, Lung, and Blood Institute (R01HL140976)
National Heart, Lung, and Blood Institute (K01HL137557)
National Heart, Lung, and Blood Institute (K01HL160146)
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Article History
Received: 10 April 2025
Accepted: 25 June 2026
First Online: 4 July 2026
Declarations
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: Approval was obtained from the Institutional Review Board (IRB) of the Albert Einstein College of Medicine (IRB# 2022–14425), which serves as the overall IRB approval for this study. The study was reviewed and approved by IRBs at all participating institutions (approval for the multi-omics analysis, Albert Einstein College of Medicine, 2022–14425; Bronx site, Biomedical Research Alliance of New York, 21–02-210-01E; Pittsburgh site, University of Pittsburgh, STUDY21050072; Chicago site, Northwestern University, STU00022906; Baltimore site and DACC, Johns Hopkins Bloomberg School of Public Health, 16882 and 23015; Los Angeles site, University of California, Los Angeles, 20–002292-AM-00001). All participants provided written informed consent. The research conformed to the principles of the Helsinki Declaration.
: Not applicable.
: T.T.B. has served as a consultant to ViiV Healthcare, Merck, EMD-Serono, and GSK. Other authors have nothing to disclose.
