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Article History

Received: 29 November 2018

Accepted: 7 May 2019

First Online: 7 June 2019

Ethics approval and consent to participate

: The MEASURE 1 study was approved by local ethics committees of participating centers (Additional file : Table S1). Informed consent was obtained from all participating patients. The ENRADAS study was approved by the central ethics committee in Berlin (Ethikkommission des Landes Berlin, Landesamt für Gesundheit und Soziales) and by local ethics committees of participating centers. Informed consent was obtained from all participating patients. No additional approvals or consent were required from either study for the current analysis.

: Not applicable.

: J. Braun received a grant/research support from and speaker/consultant for Abbvie (Abbott), Amgen, BMS, Boehringer, Celgene, Celltrion, Centocor, Chugai, EBEWE Pharma, Medac, MSD (Schering-Plow), Mundipharma, Novartis, Pfizer (Wyeth), Roche, Sanofi-Aventis, and UCB and a consultant and speakers bureau. M. de Hooge is an employee of MdH Research. R. Landewé received a grant/research support from and a consultant/speaker for Abbott, Amgen, Centocor, Novartis, Pfizer, Roche, Schering-Plow, UCB, and Wyeth and a consultant/speaker for Ablynx, AstraZeneca, Bristol-Myers Squibb, GlaxoSmithKline, and Merck and an employee of Rheumatology Consultancy BV. M. Rudwaleit is a consultant/speaker for Abbvie, BMS, Celgene, Chugai, Janssen, MSD, Novartis, Pfizer, and UCB. T. Fox, R. Martin, B. Porter, A. Readie, and H. Richards are shareholders and employees of Novartis. D. Poddubny received a grant/research support from and a consultant/speaker for Abbvie, Janssen, MSD, Novartis, and Pfizer and a speaker/consultant for Bristol-Myers Squibb and UCB. J. Sieper received a grant/research support from AbbVie, Boehringer Ingelheim, Janssen, Novartis, Merck, Lilly, Pfizer, and UCB and is a consultant/speaker for Roche and Sun. D. van der Heijde is a consultant for AbbVie, Amgen, Astellas, AstraZeneca, BMS, Boehringer Ingelheim, Celgene, Daiichi, Eli-Lilly, Galapagos, Gilead, Janssen, Merck, Novartis, Pfizer, Regeneron, Roche, Sanofi, and UCB. H. Haibel declared no competing interests.

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