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Cytotoxic T lymphocyte-associated antigen-4-Ig (CTLA-4-Ig) suppresses Staphylococcus aureus-induced CD80, CD86, and pro-inflammatory cytokine expression in human B cells

Crossref DOI link: https://doi.org/10.1186/s13075-020-2138-x

Published Online: 2020-03-30

Published Print: 2020-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Liu, Po-Chun

Ssu, Chih-Tai

Tsao, Yen-Po

Liou, Teh-Ling

Tsai, Chang-Youh

Chou, Chung-Tei

Chen, Ming-Han

Leu, Chuen-Miin https://orcid.org/0000-0002-7248-7693
Funding

Funding for this research was provided by:

Bristol-Myers Squibb (IM101-571)

Ministry of Science and Technology (MOST 106-2320-B-010-015)
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Article History

Received: 27 September 2019

Accepted: 24 February 2020

First Online: 30 March 2020

Ethics approval and consent to participate

: This study was approved by the institutional ethics committees of Taipei Veterans General Hospital (VGHTPE, IRB approval No. 2015-06-010 AC) and National Yang-Ming University (IRB approval No. YM104088E and YM10488E-1). Informed consents were signed by all patients and healthy donors before participating in this study. All samples were collected in compliance with the Helsinki Declaration.

: Not applicable.

: This work was supported by Bristol-Myers Squibb.

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