Minamino, Hiroto
Katsushima, Masao
Hashimoto, Motomu https://orcid.org/0000-0002-9241-060X
Fujita, Yoshihito
Yoshida, Tamami
Ikeda, Kaori
Isomura, Nozomi
Oguri, Yasuo
Yamamoto, Wataru
Watanabe, Ryu
Murakami, Kosaku
Murata, Koichi
Nishitani, Kohei
Tanaka, Masao
Ito, Hiromu
Ohmura, Koichiro
Matsuda, Shuichi
Inagaki, Nobuya
Morinobu, Akio
Article History
Received: 15 December 2020
Accepted: 12 March 2021
First Online: 27 March 2021
Declarations
:
: This study was conducted according to the Declaration of Helsinki and was approved by the ethics committee of Kyoto University Graduate School and Faculty of Medicine (Approval number: R0357). In all cases, patient consent was obtained prior to sample and data collection.
: Not applicable.
: M.H., K.M. (Murata), K.N., and M.T. (Tanaka) are members of a department that is financially supported by Nagahama City, Shiga, Japan; Toyooka City, Hyogo, Japan; and five pharmaceutical companies (Tanabe-Mitsubishi, Chugai, UCB Japan, Ayumi and Asahi-Kasei). The KURAMA cohort study is supported by a grant from Daiichi Sankyo Co. Ltd. M.H. receives grants and/or speaker fees from Bristol-Meyers, Eisai, Eli Lilly, and Tanabe Mitsubishi. K.N. received a research grant from Asahi-Kasei Pharma. H.I. receives a research grant and/or speaker fee from Bristol-Myers, Kyocera, and Asahi-Kasei. K.O. has received research grants and/or speaker’s fee from Abbvie, Actelion, Asahikasei Pharma, Astellas, AYUMI, Bristol-Myers Squibb, Chugai, Daiichi-Sankyo, Eisai, Eli Lilly, GSK, Janssen, JB, Mitsubishi Tanabe, Nippon Kayaku, Nippon Shinyaku, Novartis, Sanofi, and Takeda. S.M. receives grants and/or speaker fees from Daiichi Sankyo, Asahi-Kasei, Chugai, Ayumi, and Tanabe Mitsubishi. A.M. has received speaking fees and/or research grants from Eli Lilly Japan K.K., Ono Pharmaceutical Co., Pfizer Inc., UCB Japan, AbbVie G.K., Asahi Kasei Pharma and Chugai Pharmaceutical Co. Ltd. H.M., M.K., T.Y., Y.F., K.I., N.I., Y.O., W.Y., K.M.(Murakami), H.A., and N.I. declare no conflicts of interest. The sponsors had no role in the design of the study, the collection or analysis of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. The authors, their immediate families, and any research foundations with which they are affiliated have not received any financial payments or other benefits from any commercial entity related to the subject of this article.