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Study TPX-100-5: intra-articular TPX-100 significantly delays pathological bone shape change and stabilizes cartilage in moderate to severe bilateral knee OA

Crossref DOI link: https://doi.org/10.1186/s13075-021-02622-8

Published Online: 2021-09-17

Published Print: 2021-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

McGuire, Dawn http://orcid.org/0000-0002-9759-6263
Bowes, Michael

Brett, Alan

Segal, Neil A.

Miller, Meghan

Rosen, David

Kumagai, Yoshinari
Funding

Funding for this research was provided by:

Orthotrophix, Inc
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Text and Data Mining valid from 2021-09-17

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Article History

Received: 19 February 2021

Accepted: 5 September 2021

First Online: 17 September 2021

Declarations

:

: Written informed consent was obtained prior to study enrollment. Institutional Review Board approval was obtained from Western IRB with approval ID #20131394.

: Not applicable.

: AB and MB are employees of Imorphics, Manchester, UK. DM, MM, DR, and YK are employees of OrthoTrophix, Inc., Oakland, CA. NS reports no competing interests.

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