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Authors
Li, Xiaoxiao
Wu, Ziying
Zhang, Yuqing
Zeng, Chao
Lei, Guanghua
Wei, Jie
Li, Jiatian
Xiao, Yongbing
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Funding
Funding for this research was provided by:
National Key Research and Development Program of China (2022YFC2505500)
National Key Research and Development Program of China (2022YFC3601900, 2022YFC3601901)
National Natural Science Foundation of China, China (82072502, 82372474)
Central South University Innovation-Driven Research Program (2023CXQD031)
National Natural Science Foundation of China (82430081, U21A20352)
National Natural Science Foundation of China (82472524)
Natural Science Foundation of Hunan Province (2022JJ20100)
Scientific Research Program of FuRong Laboratory (2023SK2100)
Natural Science Foundation of Hunan Province, China (2023JJ30951)
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Article History
Received: 5 June 2025
Accepted: 15 January 2026
First Online: 24 January 2026
Declarations
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: The medical ethics review boards of the University of California, San Francisco (approval number 10–00532), and the 4 clinical centers of the OAI project recognized the project as Health Insurance Portability and Accountability Act compliant. All participants provided written informed consent before enrollment in the OAI study.
: Not required.
: The authors declare no competing interests.
