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Authors
Marshall, Deborah A.
Ben, Rodrigo Dal
Currie, Gillian R.
Yeung, Rae S. M.
Vastert, Sebastiaan J.
Wulffraat, Nico
Swart, Joost F.
Benseler, Susanne
,
Tse, Shirley
Levy, Deborah
Laxer, Ronald
Feldman, Brian
Dissanayake, Dilan
Limenis, Elizaveta
Verstegen, Ruud
Spiegel, Lynn
Schneider, Rayfel
Rozenblyum, Evelyn
Ji Young Lee, Jennifer
Rachlis, Alisa
Johnson, Nicole
Dhalla, Muhammed
Miettunen, Paivi
Schmeling, Heinrike
Twilt, Marinka
Stevenson, Rebeka
Human, Andrea
Cabral, David
Guzman, Jaime
Morishita, Kim
Houghton, Kristin
Tucker, Lori
Gerschman, Tommy
Tam, Herman
Chan, Mercedes
Petty, Ross
Jurencak, Roman
Luca, Nadia
Duffy, Ciarán
El Tal, Tala
Berard, Roberta
Park, Jonathan
Demirkaya, Erkan
Lim, Lily
Huber, Adam
Lang, Bianca
Stringer, Elizabeth
DeCoste, Chelsea
Ramsey, Suzanne
Rumsey, Dax G.
Basodan, Daniah
Lim, Lillian
Yan Ng, Hon
McColl, Jeanine
McGrath, Tara
Batthish, Michelle
Cellucci, Tania
Heale, Liane
LeBlanc, Claire
Chédeville, Gaëlle
Scuccimarri, Rosie
Campillo, Sarah
Lahiry, Piya
Dancey, Paul
Blanchette, Nickolas
Rosenberg, Alan
Jariwala, Mehul
Kerr, Tristan
Neufeld, Kate
Hutchinson, Clare
Soon, Gordon
Schonenberg, Dieneke
Gruppen, Mariken
van den Berg, Merlijn
Biesbroek, Giske
van Pelt, Philomine
Verkaaik, Marleen
Kamphuis, Sylvia
Brinkman, Danielle
Hissink Muller, Petra
Schatorje, Ellen
Hoppenreijs, Esther
van Royen-Kerkhof, Annet
Prakken, Berent
Van Nieuwenhove, Erika
Jansen, Marc
Legger, Elizabeth
Armbrust, Wineke
Cafazzo, Joseph
IJzerman, Maarten
Mosoiu, Alexander
Xu, Amy
Cheng, Arthur
Pereira, Bruno
Duong, Trang
Cheng, Harper
Jebb, BrenleighJebb
Sran, Ravneet
Boudes, Elodie
Kip, Michelle
de Rook, Sytze
de Geus, Regina
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Funding
Funding for this research was provided by:
Canadian Institutes of Health Research (381280)
Genome Canada (OGI-150)
Genome Alberta
Ontario Genomics
ZonMw (848006001)
ReumaNederland
One Child Every Child
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Article History
Received: 12 September 2025
Accepted: 1 March 2026
First Online: 27 March 2026
Declarations
:
: The study complied with the Declaration of Helsinki. Ethical approval for this study was granted by the University of Calgary (Conjoint Health Research Ethics Board, REB17–1563), the Hospital for Sick Children (Clinicial Trials Ontario CTO#1771) for Canada and by the Ethical Board of Utrecht (18–474) for the Netherlands. Ethics boards in Canada are guided by the Tri-Council Policy Statement.
: N/A.
: DAM reports relationships with Illumina Inc that includes: travel reimbursement; International Society for Pharmacoeconomics and Outcomes Research Inc that includes: speaking and lecture fees and travel reimbursement; Office of Health Economics that includes: consulting or advisory; Analytica that includes: consulting or advisory; Novartis that includes: consulting or advisory; Public Health Agency of Canada that includes: board membership. RSMY reports a relationship with AstraZeneca that includes: funding or grants; Amgen that includes: funding or grants; Sobi that includes: speaking and lecture fees and travel reimbursement. SJV reports a relationship with Sobi Inc that includes: consulting or advisory, funding grants, and speaking and lecture fees; Novartis that includes: consulting or advisory and speaking and lecture fees. JFS reports a relationship with Pfizer Inc that includes: consulting or advisory, funding grants, and speaking and lecture fees; Bristol Myers Squibb Co that includes: board membership; ERN-RITA that includes: funding grants. All other authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
