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Authors
Zhang, Zhiyu
Du, Yun
Zhang, Fei
Li, Xiaoqi
Rong, Lei
Zhu, Heng
Tan, Jie
Huang, Jing
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Funding
Funding for this research was provided by:
the financial support from the National Natural Science Foundation of China (No. 82170445)
the financial support from the National Natural Science Foundation of China (No. 82170445)
the financial support from the National Natural Science Foundation of China (No. 82170445)
the financial support from the National Natural Science Foundation of China (No. 82170445)
the financial support from the National Natural Science Foundation of China (No. 82170445)
the financial support from the National Natural Science Foundation of China (No. 82170445)
the financial support from the National Natural Science Foundation of China (No. 82170445)
the financial support from the National Natural Science Foundation of China (No. 82170445)
the Major Scientific Instrument Development Project of the National Natural Science Foundation of China (No. 32127802)
the Major Scientific Instrument Development Project of the National Natural Science Foundation of China (No. 32127802)
the Major Scientific Instrument Development Project of the National Natural Science Foundation of China (No. 32127802)
the Major Scientific Instrument Development Project of the National Natural Science Foundation of China (No. 32127802)
the Major Scientific Instrument Development Project of the National Natural Science Foundation of China (No. 32127802)
the Major Scientific Instrument Development Project of the National Natural Science Foundation of China (No. 32127802)
the Major Scientific Instrument Development Project of the National Natural Science Foundation of China (No. 32127802)
the Major Scientific Instrument Development Project of the National Natural Science Foundation of China (No. 32127802)
the Medical technology innovation "Unveiling Command Project" of the Second Affiliated Hospital of Chongqing Medical University (No. 2023IIT094)
the Medical technology innovation "Unveiling Command Project" of the Second Affiliated Hospital of Chongqing Medical University (No. 2023IIT094)
the Medical technology innovation "Unveiling Command Project" of the Second Affiliated Hospital of Chongqing Medical University (No. 2023IIT094)
the Medical technology innovation "Unveiling Command Project" of the Second Affiliated Hospital of Chongqing Medical University (No. 2023IIT094)
the Medical technology innovation "Unveiling Command Project" of the Second Affiliated Hospital of Chongqing Medical University (No. 2023IIT094)
the Medical technology innovation "Unveiling Command Project" of the Second Affiliated Hospital of Chongqing Medical University (No. 2023IIT094)
the Medical technology innovation "Unveiling Command Project" of the Second Affiliated Hospital of Chongqing Medical University (No. 2023IIT094)
the Medical technology innovation "Unveiling Command Project" of the Second Affiliated Hospital of Chongqing Medical University (No. 2023IIT094)
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Article History
Received: 17 June 2025
Accepted: 22 July 2025
First Online: 30 July 2025
Declarations
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: This study included Mendelian randomization (MR) analyses using publicly available summary-level data from genome-wide association studies (GWAS), all of which had received prior ethical approval from their respective institutional review boards and obtained informed consent from participants. No new individual-level human genetic data were collected for the MR component, and no additional ethical approval was required. All animal experiments were reviewed and approved by the Animal Ethics Committee of Chongqing Medical University and conducted in accordance with institutional and national guidelines for the care and use of laboratory animals. The clinical study was approved by the Ethics Committee of Kaizhou District People’s Hospital, Chongqing (Approval No. 20240227). Written informed consent was obtained from all participants prior to enrollment.
: The authors declare no competing interests.
: Zhiyu Zhang, Yun Du, Fei Zhang, Xiaoqi Li, Lei Rong, Heng Zhu, Jie Tan, and Jing Huang declare that they have no conflict of interest.
