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METS-IR predicts new-onset stroke in older adults with stages 0–3 cardiovascular-kidney-metabolic syndrome: a prospective, multicohort, clinical study with statistical and machine learning

Crossref DOI link: https://doi.org/10.1186/s13098-025-02033-8

Published Online: 2025-12-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wang, Yikang

Yu, Qi
Funding

Funding for this research was provided by:

Natural Science Foundation of Liaoning Province (2022-YGJC-70)
License Information

Text and Data Mining valid from 2025-12-01

Version of Record valid from 2026-01-06
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Article History

Received: 24 August 2025

Accepted: 15 November 2025

First Online: 1 December 2025

Declarations

:

: This study was conducted in accordance with the Declaration of Helsinki. All participants in the study provided written consent, and CHARLS received ethical approval from the Biomedical Ethics Review Committee of Peking University (IRB00001052-11015). The NHANES protocol was approved by the Research Ethics Review Board (ERB) of the CDC. This study was conducted in accordance with the Declaration of Helsinki and approved by the Shengjing Hospital of China Medical University. All of the patients provided written informed consent.

: The authors declare no competing interests.

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