Singh, Awadhesh Kumar https://orcid.org/0000-0002-8374-4536
Seshadri, Krishna G https://orcid.org/0000-0001-5326-7110
Unnikrishnan, A G https://orcid.org/0000-0001-7603-9639
Kesavadev, Jothydev https://orcid.org/0000-0001-6522-6391
Kalra, Sanjay https://orcid.org/0000-0003-1308-121X
Joshi, Shashank R https://orcid.org/0000-0002-0990-5821
Pandit, Kaushik https://orcid.org/0000-0003-3772-2659
Sahay, Rakesh K https://orcid.org/0000-0002-5471-0695
Panikar, Vijay K https://orcid.org/0009-0007-7785-8311
Mithal, Ambrish https://orcid.org/0000-0002-0822-3212
Gadia, Smriti https://orcid.org/0009-0000-4903-7144
Anthuvan, Thamburaj https://orcid.org/0009-0004-0756-2089
Funding for this research was provided by:
USV private limited
Article History
Received: 1 October 2025
Accepted: 2 January 2026
First Online: 11 January 2026
Declarations
:
: The study protocol, informed consent form, and participant-facing materials were approved by the Institutional Ethics Committees of all the participating centers. Written informed consent was obtained from all participants prior to enrollment. The trial was prospectively registered in the Clinical Trials Registry, India (CTRI/2024/09/073221).
: Artificial intelligence tools were used only for language refinement and grammar editing during the preparation of the manuscript. No AI tools were used to develop scientific content, perform statistical analyses, generate results, or influence the study’s design or interpretation. All analyses, conclusions, and interpretations were performed independently by the authors.
: The authors declare no competing interests.