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Article History

Received: 14 October 2022

Accepted: 22 August 2023

First Online: 11 September 2023

Declarations

:

: The Coordinating Ethical Committee of the Helsinki-Uusimaa Hospital District have earlier approved both the FinnGen general study protocols and this study. The FinnGen project is approved by The Finnish Institute for Health and Welfare (THL), approval number THL/2031/6.02.00/2017, amendments THL/1101/5.05.00/2017, THL/341/6.02.00/2018, THL/2222/6.02.00/2018, THL/283/6.02.00/2019), Digital and population data service agency VRK43431/2017-3, VRK/6909/2018-3, KELA (The Social Insurance Institution of Finland) 58/522/2017, KELA 131/522/2018, KELA 70/522/2019 and Statistics Finland TK-53-1041-17.The Biobank Access Decisions for FinnGen samples and data for Auria and Helsinki biobanks include: THL Biobank BB2017_55, BB2017_111, BB2018_19, BB_2018_34, BB_2018_67, BB2018_71, BB2019_7, Helsinki Biobank HUS/359/2017, Auria Biobank AB17-5154.All participants, whose data were accessed in this, have given an informed, signed biobank consent for their data to be used anonymously for scientific purposes, and information was transferred outside of the biobanks in pseudonymized form. All electronic health records data was mined by hospital biobank employees who have signed confidentiality agreements.All authors and employees confirm that all methods were carried out in accordance with relevant guidelines and regulations.The Finnish Biobank Act from 2013 regulates all biobank operations, supervises the rights of the donors, and establishes the requirements on researchers working with the sample collections [1]. All Finnish Biobanks are members of the BBMRI.fi infrastructure (ExternalRef removed).[1] Finlex. The Finnish Biobank Act 2013.

: Not applicable.

: The authors declare no competing interests.