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Article History

Received: 7 August 2018

Accepted: 3 December 2018

First Online: 7 January 2019

Ethics approval and consent to participate

: The procedures followed were in accordance with the ethical standards of the local institutional committees on human experimentation and with the Helsinki declaration of 1975, as revised in 1983. The Institutional Review Boards of the participating institutions approved the study (Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario “A Gemelli” prot. n. 9421/18-15338/18-ID1969 and Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi prot. n. 1258/2008). Informed consent to be included in the study was obtained from all patients.

: Not applicable

: RR and AC have received speaker’s honoraria from Novartis. For the remaining authors, none were declared.

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