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Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells

Crossref DOI link: https://doi.org/10.1186/s13148-019-0617-1

Published Online: 2019-02-04

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Cypris, Olivia

Frobel, Joana

Rai, Shivam

Franzen, Julia

Sontag, Stephanie

Goetzke, Roman

Szymanski de Toledo, Marcelo A.

Zenke, Martin

Wagner, Wolfgang https://orcid.org/0000-0002-1971-3217
Funding

Funding for this research was provided by:

Else Kröner-Fresenius-Stiftung (2014_A193)

Deutsche Forschungsgemeinschaft (WA1706/8-1, WA1706/11-1)

Interdisziplinäres Zentrum für Klinische Forschung, Medizinische Fakultät der RWTH Aachen (O1-3, O1-4)
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Article History

Received: 5 November 2018

Accepted: 17 January 2019

First Online: 4 February 2019

Ethics approval and consent to participate

: Mesenchymal stromal cells were isolated from bone marrow (<i>caput femoris</i>) of patients undergoing orthopedic surgery after written consent and the study was approved by the Ethic Committee of the Use of Human Subjects at the University of Aachen (permit number: EK128/09).

: Not applicable.

: WW is cofounder of Cygenia GmbH that can provide service for various epigenetic signatures (). Apart from this, the authors have no competing interests.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.