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Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine

Crossref DOI link: https://doi.org/10.1186/s13148-019-0639-8

Published Online: 2019-04-27

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Herberg, Maria

Siebert, Susann

Quaas, Marianne

Thalheim, Torsten

Rother, Karen

Hussong, Michelle

Altmüller, Janine

Kerner, Christiane

Galle, Joerg

Schweiger, Michal R.

Aust, Gabriela http://orcid.org/0000-0002-4670-4543
Funding

Funding for this research was provided by:

BMBF (031A312)

Volkswagen Foundation

Deutsche Forschungsgemeinschaft (SCHW1605/1-1)
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Article History

Received: 21 August 2018

Accepted: 25 February 2019

First Online: 27 April 2019

Ethics approval and consent to participate

: The study protocol conforms to the ethical guidelines of the 1975 Declaration of Helsinki. We obtained ethics approval from the Landesdirektion Leipzig (TVV 53/14) for radiation of mice. Studies using human intestinal sample were approved by the ethics committees of the Universities of Duesseldorf, Bochum, and Bonn [CitationRef removed].

: All authors have approved the manuscript for submission.

: The authors declare that they have no competing interests.

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