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DNA methylome profiling of granulosa cells reveals altered methylation in genes regulating vital ovarian functions in polycystic ovary syndrome

Crossref DOI link: https://doi.org/10.1186/s13148-019-0657-6

Published Online: 2019-04-11

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Sagvekar, Pooja

Kumar, Pankaj

Mangoli, Vijay

Desai, Sadhana

Mukherjee, Srabani https://orcid.org/0000-0001-9243-4428
Funding

Funding for this research was provided by:

Department of Science and Technology, Ministry of Science and Technology (EMR/2015/001014)

Indian Council of Medical Research (NIRRH/RA/623/04-2018)
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Article History

Received: 14 January 2019

Accepted: 27 March 2019

First Online: 11 April 2019

Ethics approval and consent to participate

: Written informed consent was obtained from all study participants who gave blood, follicular fluid and cumulus granulosa cell samples, in accordance with current edition of the NIRRH Ethics Committee for Clinical Studies (Ref: D/ICEC/Sci-54/56/2018 dated May 29, 2018). This committee is recognized by Strategic Initiative for Developing Capacity in Ethical Review (SIDCER) and Forum for Ethics Review Committees in Asia and the Western Pacific Region (FERCAP).

: Not applicable.

: The authors declare that they have no competing interests.

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