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Epigenome-wide association study of whole blood gene expression in Framingham Heart Study participants provides molecular insight into the potential role of CHRNA5 in cigarette smoking-related lung diseases

Crossref DOI link: https://doi.org/10.1186/s13148-021-01041-5

Published Online: 2021-03-22

Published Print: 2021-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Yao, Chen

Joehanes, Roby

Wilson, Rory

Tanaka, Toshiko

Ferrucci, Luigi

Kretschmer, Anja

Prokisch, Holger

Schramm, Katharina

Gieger, Christian

Peters, Annette

Waldenberger, Melanie

Marzi, Carola

Herder, Christian

Levy, Daniel http://orcid.org/0000-0003-1843-8724
Funding

Funding for this research was provided by:

Open Access funding provided by the National Institutes of Health
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Article History

Received: 12 June 2020

Accepted: 28 February 2021

First Online: 22 March 2021

Declarations

:

: All participants from the FHS, KORA, InCHIANTI, and BLSA gave informed consent for participation in this study and for the collection of plasma and DNA for analysis. The FHS study protocol was approved by Boston Medical Center. The KORA study protocol was approved by the Ethics Committee of the Bavarian Medical Association, Germany. The InCHIANTI ethical approval was granted by the Instituto Nazionale Riposo e Cura Anziani institutional review board in Italy, and participants gave informed consent to participate. The BLSA has approval from the Institutional Review Board (IRB) of Medstar Research Institute.

: Not applicable.

: The authors declare that they have no competing interests.

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