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Epigenome-wide association study for dilated cardiomyopathy in left ventricular heart tissue identifies putative gene sets associated with cardiac pathology and early indicators of cardiac risk

Crossref DOI link: https://doi.org/10.1186/s13148-025-01854-8

Published Online: 2025-03-08

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Tan, Konstanze

Tay, Darwin

Tan, Wilson

Ng, Hong Kiat

Wong, Eleanor

Morley, Michael P.

Singhera, Gurpreet K.

Lee, Chang Jie Mick

Jain, Pritesh R.

Tai, Fei Li

Hanson, Paul J.

Cappola, Thomas P.

Margulies, Kenneth B.

Foo, Roger

Loh, Marie
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Article History

Received: 24 September 2024

Accepted: 28 February 2025

First Online: 8 March 2025

Declarations

:

: For each cohort, written informed consent for the research use of donated left ventricular tissue was obtained. For heart transplant recipients, consent was obtained from the transplant recipient. For brain-dead organ donors, consent was obtained from the next-of-kin. All analyses and study protocols were approved by the relevant institutional review boards.

: The authors declare no competing interests.

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