Shore, Christopher J.
Österdahl, Marc F.
Harvey, Nicholas R.
Zhao, Naisi
Kristiansen, Mark
Michaud, Dominique S.
Steves, Claire J.
Bell, Jordana T.
Duncan, Emma L.
Funding for this research was provided by:
Wellcome Leap (JBGS22\7)
National Institutes of Health (R01 CA207110)
Chronic Disease Research Foundation (CDRF-23/2020 & CDRF-22/2020)
Article History
Received: 7 November 2025
Accepted: 13 February 2026
First Online: 26 May 2026
Declarations
:
: This study was carried out under TwinsUK BioBank ethics, approved by North West – Liverpool Central Research Ethics Committee (REC reference 19/NW/0187), IRAS ID 258513. This approval supersedes earlier approvals granted to TwinsUK by the St Thomas’ Hospital Research Ethics Committee, later London – Westminster Research Ethics Committee (REC reference EC04/015), which have now been subsumed within the TwinsUK BioBank. Participants gave informed consent to participate in this study and research conformed to the principles of the Helsinki Declaration.
: The authors confirm that participant data has been fully anonymized, and therefore no specific consent to publish is required.
: The authors declare no competing interests.