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Article History

Received: 21 October 2025

Accepted: 14 February 2026

First Online: 2 March 2026

Declarations

:

: All animal experiments were approved by the Animal Welfare Ethics Committee of Southwest Medical University (Approval No. 20250098) and complied with institutional guidelines for the care and use of laboratory animals.

: Not applicable.

: We strictly adhere to the academic integrity and transparency requirements of Clinical Epigenetics. During the manuscript preparation, we utilized the AI tool DeepSeek-V3.2 solely for non-core research tasks: English grammar polishing and sentence structure optimization. No AI tools were involved in experimental design, data collection, analysis, interpretation, or conclusion derivation—all core scientific content was independently completed and validated by the authors. Every piece of content generated or optimized by AI was thoroughly reviewed, revised, and verified by the research team to ensure accuracy, scientific rigor, and consistency with the study’s findings.

: The authors declare no competing interests.