Awuah, Jonathan
Dallmeier, Dhayana
Boehm, Felix
Herdtle, Laura
Rothenbacher, Dietrich
Perez-Correa, Juan-Felipe
Wagner, Wolfgang https://orcid.org/0000-0002-1971-3217
Funding for this research was provided by:
RWTH Aachen University
Article History
Received: 30 April 2026
Accepted: 27 June 2026
First Online: 7 July 2026
Declarations
:
: The Ethics Committee of Ulm University had approved the ActiFE study and this research (application no. 318/08 and 50/12) and all participants gave written consent. For the training set, we used some blood samples from the central biobank of the medical faculty of RWTH Aachen University, which was specifically approved by the Ethics Committee of RWTH Aachen Medical School (ethics approval number EK 206/09) and all participants provided written consent.
: Not applicable.
: W. W. is a cofounder of Cygenia GmbH, which can provide services for various epigenetic signatures, including epigenetic clocks ( ). J.-F. P.-C. contributes to Cygenia, too. Apart from this, the authors have no competing interests.