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Article History

Received: 20 April 2018

Accepted: 21 December 2018

First Online: 10 January 2019

Ethics approval and consent to participate

: The Partners Healthcare Institutional Review Board approved the study. Written informed consent was obtained from all participants prior to initiation of any study procedures in accordance with Institutional Review Board guidelines.

: Not applicable.

: Some of the authors have received research salary support from Eisai Inc. (GAM), Eli Lilly and Company (GAM, KAJ, RAS), Janssen Alzheimer Immunotherapy (DMR, GAM, KAJ, RAS), Genentech (GAM), Novartis (GAM), Avid Radiopharmaceuticals (KAJ, RAS), Navidea (KAJ), and Pfizer (KAJ). Additionally, DMR has served as a consultant for Eli Lilly, Neurotrack, Biogen, and Lundbeck Pharmaceuticals, GAM has served as a consultant for Grifols Shared Services North America, Inc. and Pifzer, KAJ has served as a consultant for Bayer, GE Healthcare, Janssen Alzheimer’s Immunotherapy, Siemens Medical Solutions, Genzyme, Novartis, Biogen, Roche, ISIS Pharma, AZTherapy, GEHC, Lundberg, and Abbvie, and RAS has served as a consultant for AbbVie, Biogen, Bracket, Genentech, Lundbeck, Roche, and Sanofi. SJC and DAL have Intellectual Property for the CFAB, which is owned by the University of Miami and licensed to I-Function. SJC is also a Chief Scientific Officer of I-Function and an equity holder in I-Function. The remaining authors declare that they have no competing interests.

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