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Article History

Received: 28 December 2018

Accepted: 6 June 2019

First Online: 4 July 2019

Ethics approval and consent to participate

: All participants gave written informed consent to participate. The Medical Ethics Review Committee of the VU University Medical Center approved this study.

: Not applicable.

: TT, RO, EW, SV, DV, SG, and RB declare that they have no competing interests.FB reports grants from EU-JU IMI (AMYPAD), EU-H2020 (EuroPOND), UK MS Society, Dutch MS Society, PICTURE (MDI-NWO), NIHR UCLH Biomedical Research Center (BRC), and ECTRIMS-MAGNIMS; is a consultant to Bayer Pharma, Biogen-Idec, TEVA, Merck-Serono, Novartis, Roche, Jansen Research, Genzyme-Sanofi, IXICO Ltd., GeNeuro, Apitope Ltd., and Lundbeck.PhS has received funding and consultancy fees, through the institution, from Toyama, Probiodrug, EIP Pharma, Genentech, Roche, Medavante, and Merck. He is co-editor-in-chief of Alz Res & Ther but had no role in the review process.WvdF received grant support from ZonMW, NWO, EU-FP7, Alzheimer Nederland, CardioVascular Onderzoek Nederland, Stichting Dioraphte, Gieskes-Strijbis Fonds, Boehringer Ingelheim, Piramal Neuroimaging, Roche BV, Janssen Stellar, and Combinostics. All funding is paid to the institution. WvdF holds the Pasman chair.BvB has received research funding from the Alzheimer Association, American Health Assistance Foundation, Alzheimer Nederland, CTMM, ZonMW, Janssen Stellar, AVID Radiopharmaceuticals, NOW, and EU-FP7. In addition, he is a trainer for Piramal Neuroimaging, GE, and AVID Radiopharmaceuticals. All funding is paid to his institution.