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Article History

Received: 30 April 2021

Accepted: 3 October 2021

First Online: 18 October 2021

Declarations

:

: The study was approved by the ethical committee of the Hospital Clínic de Barcelona.Animal experiments were conducted in accordance with the Code for Methods and Welfare Considerations in Behavioral Research with Animals (Directive 2010/63/EU) and every effort was made to minimize animal suffering. Transmission experiments were developed at Centro de Investigación en Sanidad Animal (CISA-INIA-CSIC, Madrid, Spain) and they were evaluated by the Committee on the Ethics of Animal Experiments of the Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria and approved by the General Directorate of the Madrid Community Government (permit nos. PROEX 291/19 and PROEX 094/18).

: The participants or their next-of-kin provided written informed consent for the use of samples for diagnostic and research purposes.

: RSV reports personal fees from Wave pharmaceuticals and Ionis Pharmaceuticals for attending Advisory board meetings, personal fees from Roche diagnostics, Janssen, and Neuraxpharm for educational activities, and research grants to her institution from Biogen and Sage Therapeutics outside the submitted work. The other authors declare that they have no competing interests.