Document is current

Article History

Received: 3 August 2021

Accepted: 16 November 2021

First Online: 4 December 2021

Declarations

:

: All participants gave written informed consent to use medical data and biomaterials for research purposes. Ethical approval of the Amsterdam UMC VUmc medical ethical committee was in place, and the study was in accordance with the Helsinki Declaration of 1975.

: Not applicable.

: SB, IV, BDD, ZH, MZ, and NA report no conflicts of interest. WF holds the Pasman chair. WF has performed contract research for Biogen MA Inc. and Boehringer Ingelheim. WF has been an invited speaker at Boehringer Ingelheim, Biogen MA Inc., Danone, Eisai, WebMD Neurology (Medscape). WF is a consultant to Oxford Health Policy Forum CIC, Roche, and Biogen MA Inc. WF participated in an advisory board of Biogen MA Inc. WF is associate editor at Alzheimer’s, Research & Therapy. All funding is paid to her institution. HZ has served at scientific advisory boards and/or as a consultant for Abbvie, Alector, Annexon, AZTherapies, CogRx, Denali, Eisai, Nervgen, Pinteon Therapeutics, Red Abbey Labs, Roche, Samumed, Siemens Healthineers, Triplet Therapeutics, and Wave; has given lectures in symposia sponsored by Cellectricon, Fujirebio, Alzecure and Biogen; and is a co-founder of Brain Biomarker Solutions in Gothenburg AB (BBS), which is a part of the GU Ventures Incubator Program. KB has served as a consultant or at advisory boards for Abcam, Axon, Biogen, JOMDD/Shimadzu, Lilly, MagQu, Prothena, Roche Diagnostics and Siemens Healthineers, and as data monitoring committee for Julius Clinical and Novartis. All payment was made to him personally. KB is a co-founder of Brain Biomarker Solutions in Gothenburg AB (BBS), which is a part of the GU Ventures Incubator Program. JV and ES are employees of ADx NeuroSciences. EV is co-founder of ADx NeuroSciences. JD a minor stock holder of Eli Lilly and Company and inventor on the patent application used in the Lilly P-tau217 assay. CT has a collaboration contract with ADx Neurosciences and Quanterix and performed contract research or received grants from AC-Immune, Axon Neurosciences, Biogen, Brainstorm Therapeutics, Celgene, EIP Pharma, Eisai, PeopleBio, Roche, Toyama, Vivoryon. CT serves on editorial boards of Medidact Neurologi/Springer, Alzheimer Research and Therapy, Neurology: Neuroimmunology & Neuroinflammation, and is an editor of a Neuromethods book Springer. WF: Research programs of WF have been funded by ZonMW, NWO, EU-FP7, EU-JPND, Alzheimer Nederland, CardioVascular Onderzoek Nederland, Health~Holland, Topsector Life Sciences & Health, stichting Dioraphte, Gieskes-Strijbis fonds, stichting Equilibrio, Pasman stichting, Biogen MA Inc., Boehringer Ingelheim, Life-MI, AVID, Roche NL, Biogen NL, Novartis NL, Philips, Neurocast, Fujifilm, Combinostics.