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Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of Alzheimer’s disease

Crossref DOI link: https://doi.org/10.1186/s13195-022-00966-0

Published Online: 2022-02-01

Published Print: 2022-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Dodge, James C. https://orcid.org/0000-0003-4466-7213
Tamsett, Thomas J.

Treleaven, Christopher M.

Taksir, Tatyana V.

Piepenhagen, Peter

Sardi, S. Pablo

Cheng, Seng H.

Shihabuddin, Lamya S.
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Text and Data Mining valid from 2022-02-01

Version of Record valid from 2022-02-01
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Article History

Received: 28 October 2021

Accepted: 17 January 2022

First Online: 1 February 2022

Declarations

:

: All procedures involving mice were performed using protocols approved by Sanofi Institutional Animal Care and Use Committees.

: No data sets are from individuals. Not applicable.

: All authors are current or former employees of Sanofi.

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