Ornish, Dean
Madison, Catherine
Kivipelto, Miia
Kemp, Colleen
McCulloch, Charles E.
Galasko, Douglas
Artz, Jon
Rentz, Dorene
Lin, Jue
Norman, Kim
Ornish, Anne
Tranter, Sarah
DeLamarter, Nancy
Wingers, Noel
Richling, Carra
Kaddurah-Daouk, Rima
Knight, Rob
McDonald, Daniel
Patel, Lucas
Verdin, Eric
E. Tanzi, Rudolph
Arnold, Steven E.
Funding for this research was provided by:
The Alzheimer’s Drug Discovery Foundation (GC-202102-2021459, GC-202102-2021459, GC-202102-2021459)
Leonard A. Lauder & Judith Glickman Lauder
Gary & Laura Lauder
Mary Bucksbaum Scanlan Family Foundation
Laurene Powell Jobs/Silicon Valley Community Foundation
Pierre & Pamela Omidyar Fund/Silicon Valley Community Foundation
George Vradenburg Foundation/Us Against Alzheimer’s
American Endowment Foundation
Arthur M. Blank Family Foundation
DeJoria Peace Love & Happiness Foundation
Maria Shriver/Women’s Alzheimer’s Movement
Mark Pincus Family Fund/Silicon Valley Community Foundation
Milken Family Foundation
The Cleveland Clinic Foundation
Greenbaum Foundation
R. Martin Chavez
Wonderful Company Foundation
Daniel Socolow
Anthony J. Robbins/Tony Robbins Foundation
John Mackey
John & Lisa Pritzker and the Lisa Stone Pritzker Family Foundation
Ken Hubbard
Greater Houston Community Foundation
Henry Groppe
Brock & Julie Leach Family Charitable Foundation
Bucksbaum/Baum Foundation
YPO Gold Los Angeles
Lisa Holland/Betty Robertson
The Each Foundation
Moby Charitable Fund
California Relief Program
Gary & Lisa Schildhorn
McNabb Foundation
Renaissance Charitable Foumdation
Around the Table Foundation
Network for Good
Ken & Kim Raisler Foundation
Buckmaster Foundation
Miner Foundation
Craiglist Charitable Fund
Gaurav Kapadia
Healing Works Foundation/Wayne Jonas
the Center for Innovative Medicine (CIMED) at the Karolinska Institutet, Hjärnfonden, Stockholms Sjukhem, Research Council for Health Working Life and Welfare
Alzheimer Gut Microbiome Project (funded by NIA U19AG063744 & U01AG061359 & R01AG081322, funded by NIA U19AG063744 & U01AG061359 & R01AG081322)
Article History
Received: 21 February 2024
Accepted: 15 May 2024
First Online: 7 June 2024
Declarations
:
: MK is one of the Editors-in-Chief of this journal and has no relevant competing interests and recused herself from the review process. RKD is an inventor on key patents in the field of metabolomics and holds equity in Metabolon, a biotech company in North Carolina. In addition, she holds patents licensed to Chymia LLC and PsyProtix with royalties and ownership. DO and AO have consulted for Sharecare and have received book royalties and lecture honoraria and, with CK, have received equity in Ornish Lifestyle Medicine. RK is a scientific advisory board member and consultant for BiomeSense, Inc., has equity and receives income. He is a scientific advisory board member and has equity in GenCirq. He is a consultant and scientific advisory board member for DayTwo, and receives income. He has equity in and acts as a consultant for Cybele. He is a co-founder of Biota, Inc., and has equity. He is a cofounder of Micronoma, and has equity and is a scientific advisory board member. The terms of these arrangements have been reviewed and approved by the University of California, San Diego in accordance with its conflict of interest policies. DM is a consultant for BiomeSense. RT is a co-founder and equity holder in Hyperion Rx, which produces the flashing-light glasses at a theta frequency of 7.83 Hz used as an optional aid to meditation. The rest of the authors declare that they have no competing interests.
: This clinical trial was approved by the Western Institutional Review Board on 12/31/2017 (approval number: 20172897) and all participants and their study partners provided written informed consent. The trial protocol was also approved by the appropriate Institutional Review Board of all participating sites; and all subjects provided informed consent.
: Informed consent was received from all patients. All data from research participants described in this paper is de-identified.