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Article History

Received: 21 March 2024

Accepted: 22 July 2024

First Online: 30 July 2024

Declarations

:

: Ace Alzheimer Center Barcelona cohort has been approved by the ethic committee of the Hospital Clinic i Provincial de Barcelona in Barcelona, Spain in accordance with Spanish biomedical laws (Law 14/2007, July 3rd, about biomedical research; Royal Decree 1716/2011, November 18th) and followed the recommendations of the Declaration of Helsinki.

: All the samples from the Ace Alzheimer Center Barcelona cohort and the Heidelberg/Mannheim memory clinic have the informed consent of the subjects that have donated them. In the Ace Alzheimer Center Barcelona cohort, these protocols of consent have been approved previously by Ethic Committee of the Hospital Clínic (HCB/2014/0494, HCB/2016/0571, HCB/2016/0835, HCB/2017/0125 and HCB/2018/0333). The protocols have been designed in agreement with the indications of the Sociedad Española de Neurología according to the current normative for the use of clinical data and biological material and surplus of the assisted process for the biomedicine research of neurodegenerative diseases.

: S.A., W.Y., A.O., L.F., I.R., A.C., M.B., I.H., L.H., A.H., N.A., A.R., A.R., C.M.D and T.H. declared no competing interests. Margot H.M. Bakker is a full-time employee of AbbVie Deutschland GmbH & Co KG and owns AbbVie stock. Alfredo Cabrera-Socorro is full-time employee of Janssen Pharmaceutical NV, Turnhoutseweg 30, 2340 Beerse, Belgium.