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Article History

Received: 11 December 2023

Accepted: 16 November 2024

First Online: 19 December 2024

Declarations

:

: The ALFA study protocol has been approved by an independent Ethics Committee Parc de Salut Mar Barcelona and registered at Clinicaltrials.gov (ALFA Identifier: NCT01835717). The study has been conducted in accordance with the directives of the Spanish Law 14/ 2007, of 3rd of July, on Biomedical Research (Ley 14/ 2007 de Investigación Biomédica). All the participants gave written consent to participate in the study.

: Not applicable.

: MSC has served as a consultant and at advisory boards for Roche Diagnostics International Ltd and has given lectures in symposia sponsored by Roche Diagnostics, SLU and Roche Farma, SA MSC was granted with the project “Sex and gender role in preclinical Alzheimer’s disease: from pathophysiology to clinical trials inclusion”, funded by Roche Diagnostics International Ltd; payments were made to the institution (BBRC). MTF is the Chief Scientific Officer of the non-profit organization Women’s Brain Project. She has received in the past 2 years personal fees from Roche Diagnostics unrelated to this paper. The other co-authors report no existing potential conflicts of interest relevant to this article.