Dodich, Alessandra https://orcid.org/0000-0001-9140-0699
Panzavolta, Andrea https://orcid.org/0009-0004-9206-6206
Funghi, Giulia https://orcid.org/0000-0002-2242-6008
Meli, Claudia https://orcid.org/0000-0002-3450-2768
Festari, Cristina https://orcid.org/0000-0003-3597-5097
Chatzikostopoulos, Thanos https://orcid.org/0000-0003-0467-358X
Chicherio, Christian
Clarens, Florencia https://orcid.org/0000-0003-4334-4404
de Oliveira, Fabricio Ferreira https://orcid.org/0000-0002-8311-0859
Filardi, Marco https://orcid.org/0000-0001-9702-8314
Ibanez, Agustin https://orcid.org/0000-0001-6758-5101
Invernizzi, Laura
Lebouvier, Thibaud https://orcid.org/0000-0002-4386-6045
Logroscino, Giancarlo https://orcid.org/0000-0003-0423-3242
MacPherson, Sarah E. https://orcid.org/0000-0001-8676-6514
Manca, Riccardo https://orcid.org/0000-0003-1715-6442
Marra, Camillo https://orcid.org/0000-0003-3994-4044
Matias-Guiu, Jordi A. https://orcid.org/0000-0001-8162-9043
Montembeault, Maxime https://orcid.org/0000-0003-0974-2783
Papagno, Costanza https://orcid.org/0000-0002-3659-6294
Pomati, Simone https://orcid.org/0000-0001-8930-6361
Possenti, Mario
Piguet, Olivier https://orcid.org/0000-0002-6696-1440
Sacco, Leonardo https://orcid.org/0000-0002-9494-7742
Schild, Ann-Katrin https://orcid.org/0000-0002-1920-0198
Sollberger, Marc https://orcid.org/0000-0001-8863-3731
Tábuas-Pereira, Miguel https://orcid.org/0000-0002-3988-614X
Tsatali, Marianna https://orcid.org/0000-0002-5972-8616
Tsolaki, Magda https://orcid.org/0000-0002-2072-8010
van den Berg, Esther https://orcid.org/0000-0002-8120-7366
Cappa, Stefano F. https://orcid.org/0000-0003-1003-3925
Bertoux, Maxime https://orcid.org/0000-0002-5283-503X
Kumfor, Fiona https://orcid.org/0000-0002-3208-075X
Van den Stock, Jan https://orcid.org/0000-0001-5756-3195
Boccardi, Marina https://orcid.org/0000-0001-6744-8246
Welsh-Bohmer, Kathleen Anne https://orcid.org/0000-0003-1824-0179
Cerami, Chiara https://orcid.org/0000-0003-1974-3421
,
Agosta, Federica
Canu, Elisa
Almkvist, Ove
Hagman, Goran
Winblad, Bengt
Altomare, Daniele
Angioni, Davide
Annoni, Jean-Marie
Beretta, Luca
Berres, Manfred
Bessi, Valentina
Fimm, Ingo
Kilimann, Ingo
Bora, Emre
Brioschi-Guevara, Andrea
Buchmann, Andreas
Gietl, Anton
Bussè, Cinzia
Cagnin, Annachiara
Chander, Russell
Kliegel, Matthias
Mella, Nathalie
Costa, Alfredo
Coulangers, Camille
Ousset, Pierre-Jean
Cupidi, Chiara
Démonet, Jean-François
Didic, Mira
Di Lorenzo, Francesco
Dubois, Bruno
Andrade, Alan Cronemberger
Fimm, Bruno
Galasko, Douglas
Girtler, Nicola
Nobili, Flavio
Pardini, Matteo
Henry, Julie
Bourdage, Renelle
Jiskoot, Lize
Poos, Jackie
Seelaar, Haaro
Klöppel, Stefan
Krebs, Christine
Kukull, Walter A.
Levy, Richard
Lima, Marisa
Luca, Antonella
Luzzi, Simona
Matarrubia, Marta Fernández
Mecocci, Patrizia
Pigliautile, Martina
Menichelli, Alina
Mitolo, Micaela
Monsch, Andreas U.
Moraitou, Despoina
Novak, Petr
Ortiz, Miriam E.
Papageorgiou, Sokratis
Scarmeas, Nikolaos
Papatriantafyllou, John
Plutino, Andrea
Quaranta, Davide
Ramakers, Inez
Rossi, Stefania
Russo, Mirella
Sensi, Stefano
Sachdev, Perminder
Salmon, David P.
Sanchez, Pilar
Schöberl, Florian
Shirk, Steven D.
Toraldo, Alessio
Venneri, Annalena
Meiberth, Dix
Gallucci, Maurizio
Kounti, Fotini
Herrero, Silvia Rodrigo
Marano, Pietro
Piccoli, Tommaso
Ahmed, Samrah
Böhm, Fabiola
Schroeter, Matthias
Vestberg, Susanna
Söntgerath, Marie
Thompson, Jennifer
Watermeyer, Tamlyn
van der Waal, Hendrick-Jan
Chrisman-Russell, Lucy
Morson, Silvana
Wolski, Lucas
Dori, Renzo
Fabbo, Andrea
Galli, Chiara
Bartels, Claudia
Geurtsen, Gert
Baglio, Francesca
Isernia, Sara
Dogdu, Cem
Ruiu, Elisa
Strijkert, Fijanne
Zimmermann, Nikki
Weidner, Wendy
Briales, Helena
Pezzati, Rita
Oksengard, Anne Rita
Bradshaw, Angela
Article History
Received: 3 April 2025
Accepted: 3 November 2025
First Online: 6 December 2025
Declarations
:
: The study protocol was approved by the IUSS University Ethics Committee (IUSS-University of Pavia; Protocol 104/22).
: Not applicable.
: Stefano Cappa has received speaker honoraria from Biogen, Roche and Nutricia and is member of the Scientific Advisory Board of Brain Control. Chiara Cerami has been granted for consultancy by Newel Health, LinkForMed, Ethos, Biogen Italia, Eisai. Alessandra Dodich has received funding through her institution from Associazione Alzheimer Trento ODV. Cristina Festari has received funding through her institution from the Alzheimer’s Association and Italian Ministry of Health. Giancarlo Logroscino has served as investigator for clinical trials sponsored by Biogen Pharmaceuticals, Axovant, Alector, Denali, Roche, Eisai, Genentech, Amylyx, Piam Farmaceutici SpA and has been granted for speech and consultancy by Eisai, Roche, Lilly, Piam Farmaceutici Spa, Biogen. Jordi Matias-Guiu has been granted for speech and consultancy by Almirall, Alter, Fujirebio, Esteve, KRKA and Schwabbe, Araclon, Eisai, and Schwabbe and is supported by grants from Instituto de Salud Carlos III and Fundacion Conocimiento Madri + D. Fabricio Ferreira de Oliveira has been granted for consultancy by Gerson Lehrman Group, Atheneum Partners, Guidepoint, Lionbridge. He is supported by FAPESP – The State of São Paulo Research Foundation (Grant #2015/10109–5) and is a board member of AAN Global Strategies Subcommittee, Awards Committee of the International Parkinson and Movement Society, ISTAART PIA Biofluid Based Biomarkers working group, ISTAART PIA Neuropsychiatric Syndromes and ESF Committee of Experts. Leonardo Sacco has served as investigator for clinical trials sponsored by Biogen and was member of the Advisory Board of Roche and Eisai. Agustin Ibanez is funded by ANID/FONDECYT Regular (1250091, 1210176, 1220995); ANID/FONDAP 15150012; ANID/PIA/ANILLOS ACT210096; ANID/FONDAP 15150012; Takeda CW2680521 and the Multi-Partner Consortium To Expand Dementia Research In Latin America [ReDLat, supported by Fogarty International Center (FIC) and National Institutes of Health, National Institutes of Aging (R01 AG057234, R01 AG075775, R01 AG21051, R01 AG083799, CARDS-NIH), Alzheimer’s Association (SG-20-725707), Rainwater Charitable foundation – Tau Consortium, the Bluefield Project to Cure Frontotemporal Dementia, and Global Brain Health Institute]. The contents of this publication are solely the responsibility of the author and do not represent the official views of these institutions. The funders had no role in study design, data collection, analysis, publication decision, or manuscript preparation. Marc Sollberger has been granted for speech and consultancy by Lilly, Eisai, OM Pharma. Katheen Welsh-Bohmer is a consultant to WCG, Senaptec, Jigsawdio. She serves on the U.S. POINTER data safety monitoring board and is unpaid board member for the nonprofit Dementia Alliance of NC (DANC). She is also funded through US Federal Grants (NIA/NIH), NC DHHS state funds, and private foundational support (National Philanthropic Trust/Gates to the Alzheimer’s Data Discovery Initiative ADDI). The other authors do not declare any conflict of interest.