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Article History

Received: 6 October 2025

Accepted: 12 February 2026

First Online: 20 February 2026

Declarations

:

: All procedures were performed under the approval of Veterinary Directorate of Prefecture of Heraklion (Crete) and carried out in compliance with Greek Government guidelines and the guidelines of FORTH ethics committee and were performed in accordance with approved protocols from the Federation of European Laboratory Animal Science Associations (FELASA) and Use of Laboratory animals [License number: EL91-BIOexp-02), Approval Code: 360667, Approval Date: 29/11/2021 (active for 3 years)]. All research activities strictly adhered to the EU adopted Directive 2010/63/EU on the protection of animals used for scientific purposes.

: The authors declare no competing interests.