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Article History

Received: 10 July 2024

Accepted: 31 December 2024

First Online: 29 January 2025

Declarations

:

: All procedures were conducted according to the principles expressed in the Declaration of Helsinki. Written informed consent was obtained from all participants prior to inclusion. The prospective analysis was approved by our institutional review boards (Technical University of Munich: Ref.-No.185/18 S and Ludwig-Maximilians-University Munich: Ref.-No. 18-657). The study was retrospectively registered at the DRKS (German Clinical Trials Register, DRKS00020761). Written informed consent was obtained from all subjects (patients) in this study.

: Not applicable.

: There is a partial overlap in the patient cohort with two previously published studies: 1. Schwarting et al []. 2. Probst et al []. In the Insights into Imaging paper, the research focused on detecting bone edema in apical periodontitis. However, our current study extends this by defining cutoff values for edema volume that can be detected in conventional imaging modalities, emphasizing the significance of water-sensitive MRI sequences for secondary prevention in dental practice. This novel approach provides crucial insights into the diagnostic thresholds that were not addressed in the previous studies.

: The authors declare that they have no competing interests.