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Effects of senolytic drugs on human mesenchymal stromal cells

Crossref DOI link: https://doi.org/10.1186/s13287-018-0857-6

Published Online: 2018-04-18

Published Print: 2018-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Grezella, Clara

Fernandez-Rebollo, Eduardo

Franzen, Julia

Ventura Ferreira, Mónica Sofia

Beier, Fabian

Wagner, Wolfgang https://orcid.org/0000-0002-1971-3217
Funding

Funding for this research was provided by:

Else Kröner-Fresenius-Stiftung (2014_A193)

Deutsche Forschungsgemeinschaft (WA 1706/8-1)

Bundesministerium für Bildung und Forschung (01KU1402B)
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Article History

Received: 13 February 2018

Revised: 26 March 2018

Accepted: 28 March 2018

First Online: 18 April 2018

Ethics approval and consent to participate

: Mesenchymal stromal cells were isolated from the femoral bone marrow of three donors after orthopaedic surgery. All samples were taken after informed and written consent and the study was approved by the ethics committee of RWTH Aachen University Medical School (permit number: EK300/13).

: RWTH Aachen Medical School has applied for a patent for the Epigenetic-Senescence-Signature. WW is cofounder of Cygenia GmbH that can provide services for this assay (). Apart from these, the authors declare no competing financial interests.

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