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Exosomes derived from human adipose mesenchymal stem cells improve ovary function of premature ovarian insufficiency by targeting SMAD

Crossref DOI link: https://doi.org/10.1186/s13287-018-0953-7

Published Online: 2018-08-09

Published Print: 2018-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Huang, Boxian https://orcid.org/0000-0001-9913-9077
Lu, Jiafeng

Ding, Chenyue

Zou, Qinyan

Wang, Wei

Li, Hong
Funding

Funding for this research was provided by:

Suzhou introduce expert team of clinical medicine (SZYJTD201708)

Suzhou key medicine center (SZZX201505)

Jiangsu Provincial medical innovation team (CXTDB2017013)

Maternal and health care project of Jiangsu Province-assisted reproduction medicine center (FKX201224)
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Article History

Received: 1 May 2018

Revised: 26 June 2018

Accepted: 6 July 2018

First Online: 9 August 2018

Ethics approval and consent to participate

: The use of human ovarian granular cells and human peripheral blood mononuclear cells was in accordance with the relevant guidelines and regulations, and the experimental protocols were approved by the Medical Ethics Committee of the Suzhou Hospital Affiliated to Nanjing Medical University (NJMU-2015-014). All of the patients provided written informed consent prior to participation in this study. Our investigation using experimental animals was conducted on the basis of the Nanjing Medical University Animal Center’s specific guidelines and standards.

: Not applicable.

: The authors declare that they have no competing interests.

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