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Human mesenchymal stem cells improve rat islet functionality under cytokine stress with combined upregulation of heme oxygenase-1 and ferritin

Crossref DOI link: https://doi.org/10.1186/s13287-019-1190-4

Published Online: 2019-03-12

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Laporte, Camille https://orcid.org/0000-0003-1577-3156
Tubbs, Emily

Cristante, Justine

Gauchez, Anne-Sophie

Pesenti, Sandra

Lamarche, Frédéric

Cottet-Rousselle, Cécile

Garrel, Catherine

Moisan, Anaick

Moulis, Jean-Marc

Fontaine, Eric

Benhamou, Pierre-Yves

Lablanche, Sandrine
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Article History

Received: 30 August 2018

Revised: 14 February 2019

Accepted: 25 February 2019

First Online: 12 March 2019

Ethics approval and consent to participate

: Rat islet isolation was performed in accordance with the European Council Directive 2010/63/UE and the recommendations of the French Ministry of Agriculture (2013–118) on the care and use of laboratory animals. Procedures were approved (n°9998_LBFA-U1055) by the local ethic committee and agreed by the French Ministry of Research. All protocols were carried out in the Animal facility of the Department of Biology of the University (D3842110001).Mesenchymal stem cells were isolated from bone marrow aspirated from human healthy donors who gave their written informed consent. All procedures complied with the French public health code (Article L1241–1).

: Not applicable.

: The authors declare that they have no competing interests.

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