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Article History

Received: 6 August 2019

Revised: 9 November 2019

Accepted: 20 November 2019

First Online: 4 December 2019

Ethics approval and consent to participate

: This study followed the ethical precepts of the Declaration of Helsinki (Fortaleza, Brazil, Oct 2013) and was approved by our local ethics committee (CEI, Hospital Clinic de Barcelona; Ref 7365-12). Human samples were obtained, processed, and analyzed according to current guidance in relation to the collection and preservation of human tissues for clinical use (EEC regulations 2004/23/CE and 2006/17/CE). These samples were treated in accordance with the protocol and legal requirements for the use of biological samples and biomedical research in Spain (Law 14/2007 and RD 1716/2011) and following the agreement on the use of human donated tissue for ocular transplantation, research, and future technologies (The Barcelona Principles; ). In addition, the acquisition, processing, and preservation of the tissues of this study are in accordance with the Spanish Laws for the Development and Applications of Organ Transplants (RD 9/2014). All the information provided before donation, together with informed consent, stressed that the samples obtained were to be used for clinical application and/or applied research. The use, protection, communication, and transfer of personal data complied with local regulations (Law 03/2018).

: Not applicable. This manuscript does not contain data from any individual person.

: The authors declare that they have no competing interests.