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Metformin combats high glucose-induced damage to the osteogenic differentiation of human periodontal ligament stem cells via inhibition of the NPR3-mediated MAPK pathway

Crossref DOI link: https://doi.org/10.1186/s13287-022-02992-z

Published Online: 2022-07-15

Published Print: 2022-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zhang, Yi-Lin

Liu, Fen

Li, Zhi-Bang

He, Xiao-Tao

Li, Xuan

Wu, Rui-Xin

Sun, Hai-Hua

Ge, Shao-Hua

Chen, Fa-Ming https://orcid.org/0000-0002-8398-2104
An, Ying
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (81991503, 82170926)

Natural Science Foundation of Shaanxi Province (2021JM-243)

the Young Science and Technology Nova Plan of Shaanxi Province (2021KJXX-24)

Natural Science Basic Research Program of Shaanxi Province (2020JQ-447)
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Text and Data Mining valid from 2022-07-15

Version of Record valid from 2022-07-15
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Article History

Received: 3 January 2022

Accepted: 23 May 2022

First Online: 15 July 2022

Declarations

:

: The experimental protocol of this study was approved by the Ethics Committee of the Stomatological Hospital of FMMU (201203), and informed consent was signed by all the subjects who donated their extracted teeth for cell isolation.

: Consent to participate/consent for publication is not applicable to this study.

: The authors declare that they have no competing interests.

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