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Notch-activated mesenchymal stromal/stem cells enhance the protective effect against acetaminophen-induced acute liver injury by activating AMPK/SIRT1 pathway

Crossref DOI link: https://doi.org/10.1186/s13287-022-02999-6

Published Online: 2022-07-16

Published Print: 2022-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Yu, Mengxue

Zhou, Min

Li, Jiahui

Zong, Ruobin

Yan, Yufei

Kong, Liangyi

Zhu, Qiang

Li, Changyong https://orcid.org/0000-0003-4001-037X
Funding

Funding for this research was provided by:

Natural Science Foundation of Hubei Province (2017CFB620)

Natural Science Foundation of Jiangsu Province (BK20190138)

Wuhan Municipal Science and Technology Bureau (2020020601012210)
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Text and Data Mining valid from 2022-07-16

Version of Record valid from 2022-07-16
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Article History

Received: 26 February 2022

Accepted: 22 April 2022

First Online: 16 July 2022

Declarations

:

: The care and use of animals were approved by the Committee of Animal Care and Use of Hubei Provincial Center for Food and Drug Safety Evaluation and Animal Experiment. Human umbilical cord-derived MSCs were obtained following informed, written patient consent, and the approval was obtained by the Institutional Ethics Review Board of Renmin Hospital of Wuhan University (Permit No: WDRY2019-G001).

: Not applicable.

: The authors declare that they have no competing interest.

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