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Stable expression of a truncated TLX variant drives differentiation of induced pluripotent stem cells into self-renewing neural stem cells for production of extracellular vesicles

Crossref DOI link: https://doi.org/10.1186/s13287-022-03131-4

Published Online: 2022-09-02

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Xu, Mingzhi

Chen, Gang

Dong, Yanan

Xiang, Shensi

Xue, Miaomiao

Liu, Yongxue

Song, Haijing

Song, Haifeng

Wang, Yi https://orcid.org/0000-0002-4954-6317
Funding

Funding for this research was provided by:

Ministry of Science and Technology of the People's Republic of China (2015ZX09501008-006, 2015ZX09501007-002-05)

National Natural Science Foundation of China (81272701/H1617, 31400733)
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Version of Record valid from 2022-09-02
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Article History

Received: 17 March 2022

Accepted: 10 August 2022

First Online: 2 September 2022

Declarations

:

: All animals were bred in the special pathogen-free (SPF) animal facility at Beijing Immunoah Pharma Tech Co. Ltd. The study was performed under the approval of the ethical committee of Beijing Immunoah Pharma Tech Co. Ltd. (approval number: IACUC2021-W0002). The animal study was carried out in strict accordance with the recommendations of the Guide for the Care and Use of Laboratory Animals of the Beijing Immunoah Pharma Tech Co. Ltd.

: Not applicable.

: All authors declare that there are no conflicts of interest.

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