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Article History

Received: 5 April 2022

Accepted: 8 March 2023

First Online: 29 March 2023

Declarations

:

: The in vivo study was conducted with the full approval of the Local Ethics Committee for Animal Experiments in Wroclaw (Resolution no.069/2020/P1, 9.12.2020). The title of ethical approved project: “<i>New, two-stage scaffolds based on calcium nanoapatite (nHAP) incorporated with iron nanooxides (Fe2O3/Fe3O4) with the function of controlled release of miRNA in a static magnetic field for the regeneration of bone fractures in osteoporotic patients. In vivo assessment of the osteogenic properties of the obtained materials using the model of critical-size cranial defect in SAMP6 mice.</i>” The guidelines included in the Act on the Protection of Animals Used for Scientific or Educational Purposes from 15 of January 2015, which implements Directive 2010/63/EU of the European Parliament and the Council of 22 September 2010, were fully followed during the study. Moreover, the procedures of PN-EN ISO 10993–2:2006 standards were used. The manuscript has been checked in accordance with ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) in order to improve the reporting of research involving animals, as well as maximise the quality and reliability of published research.

: Not applicable.

: The authors declare that they have no competing interests.