Li, Zhi-Ling
Li, Xiao-Tong
Hao, Rui-Cong
Wang, Fei-Yan
Wang, Yu-Xing
Zhao, Zhi-Dong
Li, Pei-Lin
Yin, Bo-Feng
Mao, Ning
Ding, Li
Zhu, Heng http://orcid.org/0000-0002-8408-3821
Funding for this research was provided by:
National Natural Sciences Grants China (82172388, 81871771)
Key Technology Research and Development Program of Shandong (2022YFA1104100, 2022YFA1103500)
Natural Science Foundation of Beijing Municipality (7222123, L212065)
Article History
Received: 5 January 2023
Accepted: 7 July 2023
First Online: 27 September 2023
Declarations
:
: The animal research involved in this work was approved by the Institutional Animal Care and Use Committee of Military Medical Sciences. Title of the approved project: National Science Foundation for “The regulatory effects of chondrogenic progenitor cells on the osteoclast formation and bone remodeling in osteoarthritis”. The initial Ethics approval (IACUC-DWZX-2021-545) was obtained on March 1, 2021. The care and use of animals were performed strictly following the regulations on the management of experimental animals. The research on human PBMC samples involved in this work was approved by the Research Ethics Committee of Military Medical Sciences, PLA. Title of the approved project: National Science Foundation for “A study of chondrogenic progenitor cells suppress osteoclast formation and regulate osteoarthritic bone remodeling via secretory ubiquitin-editing enzyme A20 and their underlying mechanisms”. The initial Ethics approval (AF/SC-08102.83) was obtained on March 9, 2021. The research on human tibia plateau specimens and OASF samples involved in this work was approved by the Institutional Review Board at the Chinese People’s Liberation Army General Hospital Title of the approved project: “discarded biological material from knee osteoarthritis patients with total knee arthroplasty for scientific research projects.” The initial Ethics approval (2018-03-15) was obtained on March 15, 2018.
: Not applicable.
: The authors declare that they have no competing interests.