Zhang, Lili
Thalakiriyawa, Dineshi Sewvandi
Liu, Jiawei
Yang, Shengyan
Wang, Yan
Dissanayaka, Waruna Lakmal https://orcid.org/0000-0002-3621-4866
Funding for this research was provided by:
Research Grants Council, University Grants Committee (General Research Fund: 17117619)
Article History
Received: 26 October 2024
Accepted: 14 January 2025
First Online: 26 January 2025
Declarations
:
: This study was performed according to the institutional guidelines. The experimental procedures were carried out in accordance with the protocol entitled “The Hif-1α-SEMA4D-Plexin-B1 signaling axis regulates dental stem cells in the stabilization of vascular structures”, which was initially approved by the Committee on the Use of Live Animals in Teaching and Research (CULATR), The University of Hong Kong on February 21, 2019 (CULATR 4969-19), with an update on July 21, 2021 (CULATR 4969-19 1st Amendment-21). Under this approval, performing experiments using human cells, including applying them in Matrigel plugs under the subcutaneous tissue of mice, was approved. All animal experiments were performed according to the guidelines for the Care and Use of Laboratory Animals published by the US National Institutes of Health and regulations at the Laboratory Animal Unit of the University of Hong Kong. The work has been reported in line with the ARRIVE guidelines 2.0. The SHED and HUVECs were purchased from AllCells (Alameda, CA, USA) and ScienCell (Carlsbad, CA, USA), respectively. All Cells Co., Ltd and ScienCell Co., Ltd had confirmed in their certificates of analysis (COA) of the product that the ethical approval for collecting human cells was obtained, and the donors had signed informed consent. (AllCells, ; ScienCell, ).
: Not applicable.
: The authors declare no competing interests.