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Authors
Guo, Tianwei
Wang, Hongyue
Wu, Fujian
Lu, Wenjing
Zhu, Min
Ma, Shuhong
Zhang, Yongshuai
Yan, Yuting
Zhou, Meng
Talanaite, Didaer
Liu, Siyu
Qi, Man
Lan, Feng https://orcid.org/0000-0002-9038-4014
Liu, Xujie
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Funding
Funding for this research was provided by:
CAMS Innovation Fund for Medical Sciences (2021-RC310-12, 2022I2M-2-001 and 2023-I2M-1-003)
National Key Research and Devel opment Program of China (2021YFC2701703, 2023YFA0915002)
National High-Level Hospital Clinical Research Funding (2022-GSP-GG-7)
Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences (2019PT320026)
Shenzhen Fundamental Research Program (ZDSYS20200923172000001)
Open Project Fund of State Key Laboratory of Cardiovascular Diseases，Shanghai East Hospital (2024SKL-TJ001)
China Postdoctoral Science Foundation (2024T170070)
National Natural Science Foundation of China (82400381)
Open Project Fund of National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital (NCRCG-PLAGH-2024008)
Chinese PLA General Hospital Sixth medical center Innovation and Culture Grant (CXPY202304)
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Article History
Received: 7 March 2025
Accepted: 9 April 2025
First Online: 9 May 2025
Declarations
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: The H9 hESC line (WA09) used in this study was obtained from the WiCell Research Institute (Madison, WI, USA), registered with the NIH Human Embryonic Stem Cell Registry (NIH-hESC Registry Number: WAe009-A). The use of H9 hESCs complies with the National Institutes of Health (NIH) Guidelines for Human Stem Cell Research and the ethical standards outlined by the WiCell Research Institute. All experimental procedures involving H9 hESCs were conducted in accordance with the Declaration of Helsinki and the ethical guidelines for human embryonic stem cell research established by the Ministry of Science and Technology and the National Health Commission of China. No additional human subjects or embryonic materials were involved in this study.
: All authors have confirmed their consent for publication.
: The authors declare that they have no conflict of interests.
