Pi, Zhilong
Wu, You
Wu, Jingyi
Zhang, Tao
Li, Pingyue
Wang, Renkai https://orcid.org/0000-0002-3942-8739
Funding for this research was provided by:
Guangzhou Municipal Science and Technology Project (2024A03J0690)
Guangzhou Science, Technology and Innovation Commission (2023A03J0693)
Guangzhou Municipal Science and Technology Project (2024A03J0634)
Natural Science Foundation of Guangdong Province (2022A1515010307, 2024A1515012050)
Article History
Received: 1 January 2025
Accepted: 10 June 2025
First Online: 16 July 2025
Declarations
:
: This study was approved by the Medical Research Ethics Board of the General Hospital of Southern Theater Command of PLA (title: exosomal CRELD2 promotes angiogenesis and osteogenesis via the PERK-ATF4-CRELD2 pathway. Approval number: No. 2023110101. Date of approval: 20231101). All methods were carried out in accordance with relevant guidelines and regulations. HUVECs were purchased from a commercial vendor (Procell, China), which information and ethics can be found on its official website (Information and ethics can be found on its official website ().
: Not applicable.
: The authors declare that they have no conflicts of interest. The authors declare that they have not use AI-generated work in this manuscript.