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Authors
Tunstead, Courteney https://orcid.org/0000-0001-5343-7984
Bitterlich, Laura M. https://orcid.org/0000-0002-4265-6660
Ankrum, James A. https://orcid.org/0000-0003-3959-6158
Hogan, Andrew E. https://orcid.org/0000-0001-5875-230X
English, Karen https://orcid.org/0000-0002-7932-4256
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Funding
Funding for this research was provided by:
National University of Ireland, Maynooth (John & Pat Hume Doctoral Award)
Science Foundation Ireland (16/RI/3399)
Science Foundation Ireland (20/FFP-A/8948)
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Article History
Received: 23 October 2024
Accepted: 18 July 2025
First Online: 6 August 2025
Declarations
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: Ethical approval was granted by the Medical Research Ethics Committees at St Vincent’s University Hospital and by Maynooth University Ethics Committee entitled: Metabolic and Immunological Links Between Obesity, Systemic Inflammation, Type 2 Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease granted on 28th June 2024 (BSRESC-2024-38575) and Investigating the role of macrophage education by MSCs in mediating MSC therapeutic efficacy granted on 11th February 2022 (BSRESC-2022-2460651). All patients gave written informed consent prior to partaking in the study. RoosterBio (company where the human BM-MSCs were purchased) has confirmed that there was initial ethical approval for collection of human cells, and that the donors had signed informed consent. RoosterBio state “RoosterBio sources commercially available in vitro research only human bone marrow aspirate from qualified donors. All human bone marrow aspirate collections are from healthy adult consented donors. Collection protocols and the donor-informed consent document are approved by an Institutional Review Board (IRB)”.
: The authors declare that they have not used AI-generated work in this manuscript.
: The authors declare that they have no competing interests.
