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Authors
Soleymani-Goloujeh, Mehdi https://orcid.org/0000-0002-6478-3951
Babaahmadi, Mahnaz
Shekari, Faezeh
Barati, Mojgan
Fallah, Nasrin
Choshali, Mahmoud Alipour
Gholipour, Nima Makvnd
Hezavehei, Maryam
Azimi, Masoumeh
Yakhkeshi, Saeed
Vesali, Samira
Mohammadi, Saeed
Baharvand, Hossein
Hassani, Seyedeh-Nafiseh
Hajizadeh-Saffar, Ensiyeh https://orcid.org/0000-0003-4933-5250
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Funding
Funding for this research was provided by:
Royan Institute for Stem Cell Biology and Technology (RI-SCBT, Grant No. 97000135)
Iran National Science Foundation (INSF, Grant No. 97012180)
Iranian Council of Stem Cell Research and Technology (Grant No. 11/37646)
Royan Institute (RSCT, Grant NO. 97040201)
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Article History
Received: 21 December 2024
Accepted: 14 August 2025
First Online: 26 August 2025
Declarations
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: This study was conducted with the approval of the Royan Institutional Review Board and the Institutional Ethics Committee of the Royan Institute (Title: Evaluation of Extracellular Vesicles derived from pre-treated clonal BM-MSCs on β-cell regeneration and immunomodulation in type 1 diabetes murine model; Approval number: IR.ACECR.ROYAN.REC.1397.228; Date: December 04, 2018). The Iranian Blood Transfusion Organization (IBTO), as the official regulatory body, oversees the informed consent process for blood donors and ensures that all necessary approvals are obtained before sample collection. The ATMP-TDC cell banks used in this study were generated based on bone marrow samples collected with written informed consent from a healthy volunteer, in compliance with Iran Food and Drug Administration (IFDA) guidelines (Approval number: IR.ACECR.ROYAN.REC.1397.289; Date: February 19, 2019). All procedures involving human samples in this study were conducted in full compliance with the Declaration of Helsinki and relevant regulatory guidelines.
: Not applicable. This study does not include any identifiable individual data requiring consent for publication.
: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as potential conflicts of interest.
