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Authors
Tarasova, K.
Arteaga, M.B.
Kidtiwong, A.
Nivarthi, H.
Gamauf, J.
Corso, G.
Gültekin, S.
Bileck, A.
Rothbauer, M.
Toegel, S.
Hackl, M.
Kau-Strebinger, S.
Gerner, C.
Grillari, R.
Gerner, I.
Jenner, F. https://orcid.org/0000-0002-6977-1984
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Funding
Funding for this research was provided by:
wings4innovation and the KHAN-I technology transfer fund (wings4innovation and the KHAN-I technology transfer fund)
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Article History
Received: 23 May 2025
Accepted: 15 August 2025
First Online: 1 September 2025
Declarations
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: No human or animal participants were involved in this study. Ovine chondrocytes had been obtained and biobanked from sheep euthanised for reasons unrelated to this study. Based on the “Good Scientific Practice. Ethics in Science und Research” regulation implemented at the University of Veterinary Medicine Vienna, the Institutional Ethics Committee (“Ethics and Animal Welfare Committee”) of the University of Veterinary Medicine Vienna does not require approval of in vitro cell culture studies, if the cells were isolated from tissue, which was obtained either solely for diagnostic or therapeutic purposes or in the course of institutionally and nationally approved experiments. The sheep from which the cells were obtained had been euthanised in the course of a study for which approval of the national (“Commission for Animal Research” of the Austrian Federal Ministry of Science, Research and Economy) and institutional (“Ethics and Animal Welfare Committee” of the University of Veterinary Medicine Vienna”) animal welfare committees (ethical approval number: 68.205/0100-V/3b/2018, 13.7.2018) had been granted and which had been reported according to ARRIVE guidelines 2.0. Euthanasia had been conducted following sedation with detomidine and butorphanol, placement of a catheter in the jugular vein, and induction of general anesthesia with thiopental, by the administration of T61, a veterinary euthanasia drug containing tetracaine hydrochloride, mebezonium iodide, and embutramide. Human chondrocytes were provided by the ViBiMed Biobank at the Medical University of Vienna (ethics permission 1822/2017, approved by the ethics committee of the Medical University Vienna, 5.9.2017), which collects anonymized postoperative human tissue biowaste with informed consent. All methods were carried out in accordance with the relevant guidelines and regulations.
: Not applicable.
: The authors declare that they have no competing interests.
