An, Hyunji https://orcid.org/0009-0007-2853-6391
Kim, Young-Eun https://orcid.org/0009-0008-1881-3671
Jeong, Seong Dong https://orcid.org/0009-0006-5515-9766
Kim, Eun Ju https://orcid.org/0009-0004-5184-0912
Lee, Yeajin https://orcid.org/0009-0006-0538-8843
Bang, Yuna https://orcid.org/0009-0000-4211-5808
Kang, Donglim https://orcid.org/0000-0002-8025-1533
Chang, Yun-Sil https://orcid.org/0000-0001-9201-2938
Ahn, So Yoon https://orcid.org/0000-0002-1821-3173
Kim, Hyeon Ho https://orcid.org/0000-0002-0394-474X
Funding for this research was provided by:
Samsung Medical Center, Sungkyunkwan University (SMX1250031, SMX1250031)
the Ministry of Health & Welfare, Republic of Korea (KH129441)
the Ministry of Science and ICT, Republic of Korea (RS-2025-02293128)
Article History
Received: 4 June 2025
Accepted: 19 August 2025
First Online: 24 September 2025
Declarations
:
: Human Wharton’s jelly-derived MSCs were obtained from a single donor with written informed consent, under protocols approved by the Institutional Review Board of Samsung Medical Center (IRB approval number: 2016-07102-043; approval date: September 20, 2016; approval expiration date: September 15, 2025; title: Study on the selection of optimal mesenchymal stem cells from different sources for the treatment of chronic/intractable diseases including Alzheimer’s disease and musculoskeletal disorders). All animal procedures were reviewed and approved by the Institutional Animal Care and Use Committee (IACUC) of Samsung Medical Center (approval number: 20241016001) and were conducted in accordance with the National Institutes of Health Guidelines for Laboratory Animal Care as well as the institutional guidelines.All animal procedures were reviewed and approved by the Institutional Animal Care and Use Committee (IACUC) of Samsung Medical Center (Approval number: 20241016001; Approval date: October 24, 2024; Title: Investigation of the therapeutic effects and mechanisms of MSC-derived EVs in hyperoxia-induced lung injury in newborn rats) and were conducted in accordance with the National Institutes of Health Guidelines for Laboratory Animal Care as well as the institutional guidelines.
: The authors declare no competing interests.