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Authors
Maal, Alireza Beheshti
Kordi, Ramin https://orcid.org/0000-0002-0116-3018
Madani, Hoda
Khadivi, Masoud
Moghadam, Navid
Asnaashari, Ali
Najafi, Majid
Eslaminejad, Mohamadreza Baghaban
Farzanbakhsh, Shayan
Hghighatkhah, Hamidreza
Sadri, Bahareh
Karimi, Shahedeh
Hajizadeh-Saffar, Ensiyeh
Hassani, Nafiseh
Baharvand, Hossein
Vosough, Massoud https://orcid.org/0000-0001-5924-4366
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Funding
Funding for this research was provided by:
Royesh Venture Capital (Royesh Venture Capital)
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Article History
Received: 21 March 2025
Accepted: 19 August 2025
First Online: 29 September 2025
Declarations
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: This study received ethical clearance from the ethics committee of the Royan institute under the title of “Safety evaluation of intra-discal transplantation of allogeneic bone marrow derived clonal mesenchymal stromal cells (human BM-cMSCs) in patients with low back pain induced by degenerative disc disease: Interventional clinical trial, phase I” with the reference number of IR.ACECR.REC.1400.040 on the July 13th of 2021. This trial is registered in the Iranian registry of clinical trials with ID code number: IRCT20080728001031N30. The data and safety monitoring board (DSMB; Royan institute) at the Royan institute was in charge of monitoring the trial and independent experts advised researchers and clinicians. The study adhered to the principles of good clinical practice (GCP) and was carried out in accordance with the declaration of Helsinki.
: The patients included in this study provided written informed consent for the publication of anonymized data in a scientific journal. No identifiable personal information is disclosed in this manuscript.
: The authors declare that they have no conflict of interest.
: The authors declare that they have not use AI-generated work in this manuscript.
