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Article History

Received: 31 March 2025

Accepted: 28 August 2025

First Online: 25 September 2025

Declarations

:

: This study was conducted in accordance with the Declaration of Helsinki and received ethical approval from the Medical Ethics Committee of First Affiliated Hospital of Guangxi Medical University (Approval No. 2025-E0145). Written informed consent was obtained from all individual participants prior to their inclusion in the study. (1) Title of the approved project: NCAPH-YAP1 Interaction Promotes Breast Cancer Stemness and Tumor Progression; (2) Name of the institutional approval committee: Medical Ethics Committee of First Affiliated Hospital of Guangxi Medical University; (3) Approval number: 2025-E0145; (4) Date of approval: February 28, 2025. The animal experiments conducted under the protocol titled ​​"NCAPH-YAP1 Interaction Promotes Breast Cancer Stemness and Tumor Progression"​​ were approved by ​the Medical Ethics Committee of the First Affiliated Hospital of Guangxi Medical University​ (Approval No. 2024-D179-01; Date: June 1, 2024). All procedures adhered to the ​AVMA Guidelines for the Euthanasia of Animals (2020)​​ and complied with institutional and national standards for animal welfare. We had institutional approval for performing experiments using human cells. MCF10A, MCF7, MDA-MB-231, SK-BR-3, HCC1143 and MDA-MB-468 were obtained from Procell Life Science&Tech (Wuhan, China). Procell Life Science&Tech Company has confirmed that there was initial ethical approval for collection of human cells, and that the donors had signed informed consent.

: The authors declare that they have not use AI-generated work in this manuscript.

: Not applicable.

: The authors declare that they have no competing interests.